Paceman Chris Woakes (5-31) took his match bag to 11 wickets but England face a difficult run chase against Pakistan after the tourists stretched their lead to 281.
Asad Shafiq (49) and Sarfraz Ahmed (45) batted Pakistan into a strong position despite Chris Woakes taking another five-wicket haul - but dropped two catches late in the day cost them.
Earlier, Yasir Shah took 6-72 as England were bundled out quickly for just 272. Pakistan 339 and 214 for 8 (Shafiq 49, Sarfraz 45, Woakes 5-31) lead England 272 (Cook 81, Yasir 6-72) by 281 runs.
July 2016
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2016 ENG v PAK 1st TestSeries Tagged in ClipDex
2016 ENG v PAK Test serie ...Players Tagged in ClipDex
Misbah-ul-Haq Asad Shafiq Broad, Stuart C J Wahab Riaz Yasir Shah Moeen Ali Sarfraz Ahmed Woakes, Chris RGrounds Tagged in ClipDex
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